L-citrulline, like L-arginine and L-ornithine, is a metabolite in the urea cycle and is involved in liver detoxification and vasodilation pathways.* It is produced in the urea cycle when carbamoyl phosphate is converted to citrulline in the ornithine carbamoyltransferase reaction. When endogenous supplies of ornithine carbamoyltransferase are insufficient, supplemental L-citrulline has been shown to support ammonia incorporation and liver detoxification of ammonia.
Suggested Use:
As a dietary supplement, 1 and 1/4 teaspoons two times daily, or as directed by a healthcare practitioner. Contraindicated for individuals with kidney abnormalities, a hypersensitivity to L-citrulline and for children under 12 years of age.
|