L-Citrulline is involved in liver detoxification of ammonia, potentially promotes vasodilation, and has been shown to speed recovery from fatigue.* It has also been utilized in the treatment of Ornithine Transcarbamylase Deficiency and other Urea Cycle disorders.* It is produced in the urea cycle when carbamoyl phosphate is converted to citrulline in the ornithine carbamoyltransferase reaction. When endogenous supplies of ornithine carbamoyltransferase are insufficient, supplemental L-citrulline has been shown to support ammonia incorporation and liver detoxification of ammonia.* Free form amino acid, high purity, well tolerated. Hypoallergenic.
