RainTree Nutrition Graviola - Some of the active ingredients documented, researched, and verified in Graviola are a group of Annonaceous Acetogenins which are only found in the Annonaceae family to which Graviola belongs. These phytochemicals are being researched around the world for their active biological properties and potential uses.
The Annonaceae family (130 genera and 2300 species), is chemically one of the least known of the tropical plant families due to it's large size. Phytochemical and pharmacological studies on Annonaceous species have intensified in the last 15 years. This is largely due to the discovery of these Annonaceous acetogenins, a class of natural compounds with a wide variety of biological activities. To date, over 350 Annonaceous acetogenins have been isolated from 37 species of Annona plants, including Graviola. Studies show that about 50%, of over 80 Annonaceous species screened thus far, are significantly bioactive therefore, this class of compounds can be expected to continue to grow at an exponential rate in the future, provided that financial support for such research efforts can be found to study the remaining species of unscreened plants. With the demise of the world's tropical rain forests, such work is compelling before the great chemical diversity, contained within these endangered species, is lost.
In a journal article titled Annonaceous Acetogenins: Recent Progress published in the Journal of Natural Products in 1999 they stated: "The Annonaceous acetogenins are promising new antitumor and pesticidal agents that are found only in the plant family Annonaceae. Chemically, They are derivatives of long-chain fatty acids. Biologically, they exhibit their potent bioactivities through depletion of ATP levels via inhibiting complex I of mitochondria and inhibiting the NADH oxidase of plasma membranes of tumor cells. Thus, They thwart ATP-driven resistance mechanisms
PRODUCT INGREDIENTS
Sold in bottles of 100 capsules with 600 milligrams of 100% pure Graviola in each capsule. No binders or fillers.
DOSAGE
Recommended use is 2 capsules 3 times daily.
