Rheumatism and arthritis are manifested by fever, painful tenderness or soreness, lameness and swelling of the affected area. The discomfort may shift from one part to another and usually worsens in damp or cold weather. Because of this, Humphrey's derived a combination of homeopathic supplements to safely help stop the pain and discomfort. It is safe to take with other over-the-counter medications and prescription medications.